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Clinical Trials For Diabetes

Diabetes mellitus is one of the most common disease in the United States. According to a survey, over 16 million Americans are suffering from diabetes and 5.4 million are not aware of this existing disease.


It is a metabolic disorder, where human body is unable to produce or properly use insulin, a hormone required to convert sugar, starches and other food into energy, and is marked by constant high levels of blood glucose (sugar).

 

There are three main types of diabetes: Type 1 diabetes, Type 2 diabetes, and Gestational diabetes. It can and often goes undiagnosed because the symptoms seem harmless and often times are normal. Some of the common diabetes symptoms, are : frequent urination, excessive thirst, extreme hunger, unusual weight loss, increased fatigue, irritability, and blurry vision.

 

Clinical trials are the research studies performed to improve the overall patient health and care. Each trial includes, running supervised tests to check the effectiveness and safety of new drugs, procedures and/or devices. Along with this, the risks and side-effects are also evaluated during these trials.

 

A clinical trial is categorized into phases. Each of the phase has some specific to do. The first phase is designed to evaluate safety, determine a safe dosage range and identify the side effects on a small group of patients. The second phase, is performed if the first one is successful. It is then repeated with a larger group to further evaluate its effect and safety. The third phase involves examination on an ever larger group and is compared with the best current treatment while gathering more information on effect and safety. While the last phase, monitors the long-term side effects after the treatment has been marketed.



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